发明授权
- 专利标题： GABA and L-glutamic acid analogs for antiseizure treatment
- 专利标题（中）： GABA和L-谷氨酸类似物用于抗发病治疗
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申请号： US420580申请日： 1995-04-12
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公开(公告)号： US5599973A公开(公告)日： 1997-02-04
- 发明人: Richard B. Silverman , Ryszard Andruszkiewicz , Po-Wai Yuen , Denis M. Sobieray , Lloyd C. Franklin , Mark A. Schwindt
- 申请人： Richard B. Silverman , Ryszard Andruszkiewicz , Po-Wai Yuen , Denis M. Sobieray , Lloyd C. Franklin , Mark A. Schwindt
- 申请人地址： IL Evanston MI Ann Arbor
- 专利权人： Northwestern University,Warner-Lambert Company
- 当前专利权人： Northwestern University,Warner-Lambert Company
- 当前专利权人地址： IL Evanston MI Ann Arbor
- 主分类号： A61K31/197
- IPC分类号： A61K31/197 ; C07C69/34 ; C07C69/675 ; C07C229/08 ; C07C229/24 ; C07C229/28 ; C07C229/34 ; C07C247/12 ; C07C309/73 ; C07D263/22 ; C07D263/26 ; G11B20/14 ; G11B27/30 ; C07C229/00
摘要：
A compound of the formula ##STR1## wherein R.sub.1 is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R.sub.2 is hydrogen or methyl; and R.sub.3 is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are also disclosed.
公开/授权文献
- US4962676A Two axis transfer device 公开/授权日：1990-10-16
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