Invention Grant
US5648455A Antibiotic WAP-8294A, method for preparing the same and antibacterial
composition
失效
抗生素WAP-8294A,其制备方法和抗菌组合物
- Patent Title: Antibiotic WAP-8294A, method for preparing the same and antibacterial composition
- Patent Title (中): 抗生素WAP-8294A,其制备方法和抗菌组合物
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Application No.: US387322Application Date: 1995-02-13
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Publication No.: US5648455APublication Date: 1997-07-15
- Inventor: Yoshitami Ohashi , Haruhisa Hirata , Seigo Nakaya , Azusa Katou , Yuji Aiba , Naomi Kokubo , Nobuyuki Suzuki , Makoto Maeda
- Applicant: Yoshitami Ohashi , Haruhisa Hirata , Seigo Nakaya , Azusa Katou , Yuji Aiba , Naomi Kokubo , Nobuyuki Suzuki , Makoto Maeda
- Applicant Address: JPX Tokyo
- Assignee: Wakamoto Pharmaceutical Co., Ltd.
- Current Assignee: Wakamoto Pharmaceutical Co., Ltd.
- Current Assignee Address: JPX Tokyo
- Priority: JPX6-043314 19940218; JPX6-103229 19940419; JPX7-016044 19950202
- Main IPC: C12P1/04
- IPC: C12P1/04 ; A61K35/74 ; A61K38/00 ; A61P31/04 ; C07K2/00 ; C07K14/195 ; C12N1/20 ; C12R1/01
Abstract:
Antibiotics WAP-8294A, A.sub.1, A.sub.2, A.sub.4, AX, AX-8, AX-9 and AX-13 or pharmeceutically acceptable salts thereof produced by a strain belonging to the genus Lysobacter; a method for producing the foregoing antibiotic WAP-8294A comprising the steps of cultivating, in the culture medium, a microorganism belonging to the genus Lysobacter and having an ability of producing the antibiotic WAP-8294A to produce the antibiotic and accumulate it in the culture medium; then recovering the antibiotic; as well as an antibacterial composition comprising the antibiotic or pharmaceutically acceptable salts thereof are herein disclosed. The novel antibiotic WAP-8294A has an excellent therapeutic effect on infectious diseases developed by infection with Gram-positive bacteria, in particular, MRSA and, therefore, the antibiotic is effective for treating diseases including MRSA infectious diseases developed through infection with Gram-positive bacteria as infectious bacteria.
Public/Granted literature
- US5032403A Multilayer plaster Public/Granted day:1991-07-16
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