发明授权
US5672688A Immunoglobulin F.sub.c fragment bound to an alkylating, antibiotic, or
antimetabolic antitum or substance
失效
与烷基化，抗生素或抗代谢抗药物或物质结合的免疫球蛋白Fc片段
- 专利标题： Immunoglobulin F.sub.c fragment bound to an alkylating, antibiotic, or antimetabolic antitum or substance
- 专利标题（中）： 与烷基化，抗生素或抗代谢抗药物或物质结合的免疫球蛋白Fc片段
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申请号： US93885申请日： 1993-07-20
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公开(公告)号： US5672688A公开(公告)日： 1997-09-30
- 发明人: Akira Kobayashi , Takao Ando , Masahiko Fujii
- 申请人： Akira Kobayashi , Takao Ando , Masahiko Fujii
- 申请人地址： JPX Tokyo
- 专利权人： Kureha Chemical Industry Co., Ltd.
- 当前专利权人： Kureha Chemical Industry Co., Ltd.
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX4-216650 19920723
- 主分类号： A61K39/395
- IPC分类号： A61K39/395 ; A61K47/48 ; C07K16/06 ; C07K16/00 ; C07K16/18
摘要：
A composition comprising as an active ingredient a compound consisting of an immunoglobulin F.sub.c fragment and an alkylating, antibiotic, or antimetabolic antitumor substance bound thereto, and a pharmaceutically acceptable carrier is disclosed. The Fc fragment moiety in the compound is stable in a living body, and thus the activity of the antitumor substance therein is maintained over a long period.
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