发明授权
- 专利标题: Assay method for the detection of 26kd TNF prohormone
- 专利标题(中): 检测26kd TNF激素的检测方法
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申请号: US463894申请日: 1995-06-05
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公开(公告)号: US5686259A公开(公告)日: 1997-11-11
- 发明人: Michael Kriegler , Carl Perez
- 申请人: Michael Kriegler , Carl Perez
- 申请人地址: CA Emeryville
- 专利权人: Chiron Corporation
- 当前专利权人: Chiron Corporation
- 当前专利权人地址: CA Emeryville
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; A61K38/00 ; A61K39/00 ; C07K14/00 ; C07K14/52 ; C07K14/525 ; C07K16/00 ; C07K16/24 ; C12N5/10 ; C12N15/02 ; C12N15/09 ; C12P21/02 ; C12P21/08 ; C12R1/91 ; G01N33/53 ; C07K16/26 ; G01N33/58
摘要:
Cleavage site blocking antibody that binds to prohormones, preferable Tumor Necrosis Factor, thereby preventing the formation of prohormone fragment(s) by proteolysis of the prohormone, and uses of the antibody including prophylactic and therapeutic methods to treat disease, and diagnostic assays for determining the amount of the prohormone and prohormone fragments present in a patients body.
公开/授权文献
- US4486050A Rectangular tunnel boring machine and method 公开/授权日:1984-12-04
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