发明授权
- 专利标题: Method of selectively destroying neoplastic cells
- 专利标题(中): 选择性破坏肿瘤细胞的方法
-
申请号: US330523申请日: 1994-10-28
-
公开(公告)号: US5688773A公开(公告)日: 1997-11-18
- 发明人: E. Antonio Chiocca , David J. Waxman , Ming X. Wei , Xandra O. Breakefield , Ling Chen
- 申请人: E. Antonio Chiocca , David J. Waxman , Ming X. Wei , Xandra O. Breakefield , Ling Chen
- 申请人地址: MA Boston MA Boston MA Boston
- 专利权人: The General Hospital Corporation,Boston University,Dana-Farber Cancer Institute
- 当前专利权人: The General Hospital Corporation,Boston University,Dana-Farber Cancer Institute
- 当前专利权人地址: MA Boston MA Boston MA Boston
- 主分类号: C12N15/09
- IPC分类号: C12N15/09 ; A61K31/675 ; A61K35/76 ; A61K38/00 ; A61K48/00 ; A61P25/00 ; A61P35/00 ; C12N5/10 ; C12N9/02 ; C12N5/00 ; C12N15/00 ; C07N14/00
摘要:
A method for selectively killing nervous system and peripheral neoplastic cells is provided. Viral vectors are used to selectively express a cytochrome P450 gene in neoplastic cells, whose gene product targets the cells for selective killing, by rendering the cells sensitive to a chemotherapeutic agent.
公开/授权文献
- US4916533A Endoscope insertion direction detecting method 公开/授权日:1990-04-10
信息查询
IPC分类: