发明授权
US5698571A 5-HT.sub.1F mediated inhibition of neurogenic meningeal extravasation: a
method for the treatment of migraine
失效
5-HT1F介导的神经源性脑膜外渗抑制：一种治疗偏头痛的方法
- 专利标题： 5-HT.sub.1F mediated inhibition of neurogenic meningeal extravasation: a method for the treatment of migraine
- 专利标题（中）： 5-HT1F介导的神经源性脑膜外渗抑制：一种治疗偏头痛的方法
-
申请号： US318330申请日： 1994-10-05
-
公开(公告)号： US5698571A公开(公告)日： 1997-12-16
- 发明人: James E. Audia , Marlene L. Cohen , Kirk W. Johnson , Lee A. Phebus , Theresa Branchek
- 申请人： James E. Audia , Marlene L. Cohen , Kirk W. Johnson , Lee A. Phebus , Theresa Branchek
- 申请人地址： IN Indianapolis
- 专利权人： Eli Lilly and Company
- 当前专利权人： Eli Lilly and Company
- 当前专利权人地址： IN Indianapolis
- 主分类号： A61K45/00
- IPC分类号： A61K45/00 ; A61K31/00 ; A61K31/135 ; A61K31/40 ; A61K31/403 ; A61K31/4045 ; A61K31/445 ; A61K31/454 ; A61K31/4545 ; A61K31/48 ; A61P25/04 ; A61P25/06 ; A61P43/00 ; A61K31/13 ; A61K31/405
摘要：
The present invention provides a method for the treatment of migraine with compounds or compositions that are selective agonists of 5-HT.sub.1F receptors relative to other serotonin receptors that produce unwanted effects like vasoconstriction. The neurogenic meningeal extravasation that leads to the pain of migraine is inhibited.
公开/授权文献
- US5110637A Amorphous oxide film and article having such film thereon 公开/授权日：1992-05-05
信息查询
