Invention Grant
US5716824A 2'-O-alkylthioalkyl and 2-C-alkylthioalkyl-containing enzymatic nucleic
acids (ribozymes)
失效
2'-O-烷硫基烷基和含有2-C烷基硫代烷基的酶核酸（核酶）
- Patent Title: 2'-O-alkylthioalkyl and 2-C-alkylthioalkyl-containing enzymatic nucleic acids (ribozymes)
- Patent Title (中): 2'-O-烷硫基烷基和含有2-C烷基硫代烷基的酶核酸（核酶）
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Application No.: US426124Application Date: 1995-04-20
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Publication No.: US5716824APublication Date: 1998-02-10
- Inventor: Leonid Beigelman , Alex Karpeisky
- Applicant: Leonid Beigelman , Alex Karpeisky
- Applicant Address: CO Boulder
- Assignee: Ribozyme Pharmaceuticals, Inc.
- Current Assignee: Ribozyme Pharmaceuticals, Inc.
- Current Assignee Address: CO Boulder
- Main IPC: C07H19/06
- IPC: C07H19/06 ; C07H19/10 ; C07H19/16 ; C07H19/20 ; C07H21/00 ; C12N15/113 ; C12N5/10 ; A61K48/00 ; C07H21/04 ; C12Q1/68
Abstract:
A compound having the formula: ##STR1## wherein, R1 represents 2'-O-R.sub.3 -thio-R.sub.3 and/or 2'-C-R.sub.3 -thio-R.sub.3, wherein R.sub.3 is independently a moiety selected from a group consisting of alkyl, alkenyl, alkynyl, aryl, alkylaryl, carbocyclic aryl, heterocyclic aryl, amide and ester, X represents a base or H; Y represents a phosphorus-containing group; and R2 represents H, DMT or a phosphorus-containing group.
Public/Granted literature
- US4474321A Control unit for driving plural loopers Public/Granted day:1984-10-02
Information query
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