发明授权
- 专利标题: Expression system for producing apolipoprotein AI-M
- 专利标题(中): 载脂蛋白AI-M的表达系统
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申请号: US448606申请日: 1995-08-25
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公开(公告)号: US5721114A公开(公告)日: 1998-02-24
- 发明人: Lars Abrahamsen , Erik Holmgren , Christina Kalderen , Mats Lake , .ANG.sa Mikaelsson , Torsten Sejlitz
- 申请人: Lars Abrahamsen , Erik Holmgren , Christina Kalderen , Mats Lake , .ANG.sa Mikaelsson , Torsten Sejlitz
- 申请人地址: SEX Stockholm
- 专利权人: Pharmacia & Upjohn Aktiebolag
- 当前专利权人: Pharmacia & Upjohn Aktiebolag
- 当前专利权人地址: SEX Stockholm
- 优先权: SEX9203753 19921211
- 主分类号: C12N15/09
- IPC分类号: C12N15/09 ; C07K14/775 ; C12N1/21 ; C12N15/12 ; C12N15/71 ; C12P21/02 ; C12R1/19 ; C12R1/91 ; C12P21/06 ; C07H21/04 ; C12N1/20 ; C12N15/00
摘要:
The invention relates to an expression system giving high extracellular production of apolipoprotein AI-M (Milano) using E. coli and comprises a plasmid carrying an origin of replication, an inducible promoter sequence, a DNA sequence coding for a signal peptide, a DNA sequence coding for apolipoprotein AI-M, and a transcription terminator. The invention also relates to a method of producing apolipoprotein AI-M using the expression system.
公开/授权文献
- USD323525S Music box 公开/授权日:1992-01-28
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