发明授权
- 专利标题： Somatostatin receptors
- 专利标题（中）： 生长抑素受体
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申请号： US417103申请日： 1995-04-05
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公开(公告)号： US5723299A公开(公告)日： 1998-03-03
- 发明人: Graeme I. Bell , Yuichiro Yamada , Susumu Seino
- 申请人： Graeme I. Bell , Yuichiro Yamada , Susumu Seino
- 申请人地址： IL Chicago
- 专利权人： Arch Development Corporation
- 当前专利权人： Arch Development Corporation
- 当前专利权人地址： IL Chicago
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; A61K39/395 ; C07K14/575 ; C07K14/655 ; C07K14/705 ; C07K14/72 ; C07K16/00 ; C12N1/19 ; C12N1/21 ; C12N5/10 ; C12N15/00 ; C12N15/09 ; C12N15/12 ; C12P21/02 ; C12P21/08 ; C12R1/91 ; G01N33/566
摘要：
The invention relates generally to compositions of and methods for obtaining somatostatin receptors. The invention relates as well to the DNA sequences encoding somatostatin receptors, the recombinant vectors carrying those sequences, the recombinant host cells including either the sequences or vectors, and recombinant somatostatin receptor polypeptides. By way of example, the invention discloses the cloning and functional expression of at least three different somatostatin receptors, SSTR1, SSTR2 and SSTR3 from two different mammalian sources. The invention includes as well, methods for using the isolated, recombinant receptor polypeptides in assays designed to select and improve substances capable of interacting with somatostatin receptor polypeptides for use in diagnostic, drug design and therapeutic applications.
公开/授权文献
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