发明授权
- 专利标题： High purity albumin and method of producing
- 专利标题（中）： 高纯度白蛋白和生产方法
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申请号： US378859申请日： 1995-05-25
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公开(公告)号： US5728553A公开(公告)日： 1998-03-17
- 发明人: Andrew R. Goodey , Darrell Sleep , Hendrik van Urk , Stephen Berezenko , John R. Woodrow , Richard A. Johnson , Patricia C. Wood , Steven J. Burton , Alan V. Quirk , David St. J. Coghlan , Mark J. Wilson
- 申请人： Andrew R. Goodey , Darrell Sleep , Hendrik van Urk , Stephen Berezenko , John R. Woodrow , Richard A. Johnson , Patricia C. Wood , Steven J. Burton , Alan V. Quirk , David St. J. Coghlan , Mark J. Wilson
- 申请人地址： GBX Nottingham
- 专利权人： Delta Biotechnology Limited
- 当前专利权人： Delta Biotechnology Limited
- 当前专利权人地址： GBX Nottingham
- 主分类号： C12P21/02
- IPC分类号： C12P21/02 ; A61K9/08 ; A61K47/42 ; A61P7/08 ; A61P17/02 ; C07K14/76 ; C07K14/765 ; C12N1/19 ; C12N15/14 ; B01J39/06 ; B01J41/06
摘要：
A process for the preparation of albumin which has extremely low levels of or is essentially free of colorants, metal ions, human proteins, fragments of albumin, polymers or aggregates of albumin, and viruses, and which is relatively non-glycated, relatively high in free thiol and with an intact C-terminus. The process comprises passing albumin (preferably expressed and secreted by transformed yeast) through two chromatography purifications, ultrafiltering the product, passing through two further chromatography steps and again ultrafiltering the product.
公开/授权文献
- USD276627S Dispensing machine or the like 公开/授权日：1984-12-04
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