发明授权
US5759841A Immunological composition of measles virus utilizing recombinant poxvirus
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使用重组痘病毒的麻疹病毒的免疫组成
- 专利标题: Immunological composition of measles virus utilizing recombinant poxvirus
- 专利标题(中): 使用重组痘病毒的麻疹病毒的免疫组成
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申请号: US487412申请日: 1995-06-07
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公开(公告)号: US5759841A公开(公告)日: 1998-06-02
- 发明人: Enzo Paoletti , Jill Taylor
- 申请人: Enzo Paoletti , Jill Taylor
- 申请人地址: NY Troy
- 专利权人: Virogenetics Corporation
- 当前专利权人: Virogenetics Corporation
- 当前专利权人地址: NY Troy
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; C07K14/015 ; C07K14/02 ; C07K14/03 ; C07K14/035 ; C07K14/045 ; C07K14/05 ; C07K14/06 ; C07K14/065 ; C07K14/07 ; C07K14/11 ; C07K14/12 ; C07K14/125 ; C07K14/145 ; C07K14/15 ; C07K14/155 ; C07K14/16 ; C07K14/175 ; C07K14/18 ; C07K14/33 ; C12N15/863 ; C12N7/00 ; A61K39/12 ; A61K39/155 ; C12N15/00
摘要:
What is described is a recombinant poxvirus, such as vaccinia virus or canarypox virus, containing foreign DNA from Morbillivirus. In one embodiment, the foreign DNA is expressed in a host by the production of a measles virus glycoprotein. In another embodiment, the foreign DNA is expressed in a host by the production of at least two measles virus glycoproteins. What is also described is a vaccine containing the recombinant poxvirus for inducing an immunological response in a host animal inoculated with the vaccine. By the present invention, cross-protection of dogs against canine distemper is obtained by inoculating the dog with the recombinant poxvirus.
公开/授权文献
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