发明授权
US5786322A Peptides and compounds that bind selectins including endothelium
leukocyte adhesion molecule 1
失效
结合选择素的肽和化合物，包括内皮细胞粘附分子1
- 专利标题： Peptides and compounds that bind selectins including endothelium leukocyte adhesion molecule 1
- 专利标题（中）： 结合选择素的肽和化合物，包括内皮细胞粘附分子1
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申请号： US485508申请日： 1995-06-07
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公开(公告)号： US5786322A公开(公告)日： 1998-07-28
- 发明人: Ronald W. Barrett , Steven E. Cwirla , William J. Dower , Kerry J. Koller , Jung Lee , Christine L. Martens , Beatrice Ruhland-Fritsch
- 申请人： Ronald W. Barrett , Steven E. Cwirla , William J. Dower , Kerry J. Koller , Jung Lee , Christine L. Martens , Beatrice Ruhland-Fritsch
- 申请人地址： GB2 Greenford
- 专利权人： Affymax Technologies N.V.
- 当前专利权人： Affymax Technologies N.V.
- 当前专利权人地址： GB2 Greenford
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K47/48 ; A61K49/00 ; A61K51/08 ; C07K1/04 ; C07K7/06 ; C07K7/08 ; C07K14/00 ; C07K5/00 ; C07K7/00 ; C07K16/00
摘要：
Disclosed are peptides and peptide mimetics that bind selectins, including endothelial leukocyte adhesion molecule 1 (ELAM-1). Such peptides and peptide mimetics are useful in methods for blocking adhesion of leukocytes to the selectins for the purpose of inhibiting inflammation as well as in diagnostic methods employing labeled peptides and peptide mimetics that bind selectins for the purpose of determining the site of inflammation in mammals which inflammation is mediated by the presence of one or more selectins.
公开/授权文献
- US5037711A Assembly of accumulator cells juxtaposed to form a unit 公开/授权日：1991-08-06
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