发明授权
- 专利标题: Immunoglobulin variants
- 专利标题(中): 免疫球蛋白变体
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申请号: US934373申请日: 1992-08-21
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公开(公告)号: US5821337A公开(公告)日: 1998-10-13
- 发明人: Paul J. Carter , Leonard G. Presta
- 申请人: Paul J. Carter , Leonard G. Presta
- 申请人地址: CA South San Francisco
- 专利权人: Genentech, Inc.
- 当前专利权人: Genentech, Inc.
- 当前专利权人地址: CA South San Francisco
- 主分类号: C07K16/00
- IPC分类号: C07K16/00 ; A61K38/00 ; A61K39/395 ; A61P35/00 ; C07K14/00 ; C07K16/18 ; C07K16/28 ; C07K16/32 ; C07K16/46 ; C07K19/00 ; C12N15/09 ; C12N15/13 ; C12P21/08 ; C12R1/19 ; C12R1/91 ; G06F15/00
摘要:
Variant immunoglobulins, particularly humanized antibody polypeptides are provided, along with methods for their preparation and use. Consensus immunoglobulin sequences and structural models are also provided.
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