- 专利标题： HIV protease inhibitors
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申请号： US478934申请日： 1995-06-07
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公开(公告)号： US5827859A公开(公告)日： 1998-10-27
- 发明人: Vincent J. Kalish , Siegfried Heinz Reich , Michael J. Rodriguez , John H. Tatlock
- 申请人： Vincent J. Kalish , Siegfried Heinz Reich , Michael J. Rodriguez , John H. Tatlock
- 专利权人： Agouron Pharmaceuticals, Inc.
- 当前专利权人： Agouron Pharmaceuticals, Inc.
- 主分类号： C07D295/20
- IPC分类号： C07D295/20 ; A61K31/00 ; A61K31/165 ; A61K31/33 ; A61K31/40 ; A61K31/403 ; A61K31/404 ; A61K31/435 ; A61K31/4353 ; A61K31/4365 ; A61K31/4427 ; A61K31/4433 ; A61K31/445 ; A61K31/4465 ; A61K31/47 ; A61K31/472 ; A61K31/4725 ; A61K31/4738 ; A61K31/4743 ; A61K31/495 ; A61K31/535 ; A61K31/5375 ; A61K31/675 ; A61P29/00 ; A61P31/00 ; A61P31/12 ; A61P31/18 ; A61P43/00 ; C07C237/42 ; C07C323/42 ; C07C323/60 ; C07D207/16 ; C07D209/08 ; C07D211/60 ; C07D211/62 ; C07D213/40 ; C07D213/56 ; C07D213/81 ; C07D215/48 ; C07D215/50 ; C07D217/02 ; C07D217/06 ; C07D217/26 ; C07D233/66 ; C07D233/90 ; C07D295/205 ; C07D401/06 ; C07D401/12 ; C07D401/14 ; C07D403/12 ; C07D403/14 ; C07D409/12 ; C07D417/12 ; C07D471/04 ; C07D495/04 ; C07F9/12 ; C07F9/62 ; C07K5/00 ; A01N43/42
摘要：
HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.
公开/授权文献
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