发明授权
US5851524A Human monoclonal anti-rhesus (D) antibodies and cell lines producing same
失效
人单克隆抗体(D)抗体和产生相同的细胞系
- 专利标题: Human monoclonal anti-rhesus (D) antibodies and cell lines producing same
- 专利标题(中): 人单克隆抗体(D)抗体和产生相同的细胞系
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申请号: US798444申请日: 1997-02-10
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公开(公告)号: US5851524A公开(公告)日: 1998-12-22
- 发明人: Roland Beliard , Ulf Bethke , Dominique Bourel , Ahmed Bouzidi , Herve Broly , Peter Byrne , Magali Holuigue , Michael Kloft , Detlef Rohm
- 申请人: Roland Beliard , Ulf Bethke , Dominique Bourel , Ahmed Bouzidi , Herve Broly , Peter Byrne , Magali Holuigue , Michael Kloft , Detlef Rohm
- 申请人地址: FRX Lille DEX Dreieich
- 专利权人: Association pour l'Essor de la Transfusion Sanguine dans la Region du Nord,BIOTEST Pharma GmbH
- 当前专利权人: Association pour l'Essor de la Transfusion Sanguine dans la Region du Nord,BIOTEST Pharma GmbH
- 当前专利权人地址: FRX Lille DEX Dreieich
- 优先权: FRX9207893 19920626; DEX4224357.2 19920723
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; C07K16/34 ; C12N5/28 ; C12P21/08 ; A61K39/395 ; C07K16/00 ; C12N5/00
摘要:
The invention relates to 2 human monoclonal antibodies of sub-classes IgG1 and IgG3, against the Rhesus D antigen and to a pharmaceutical composition containing a mixture of the said antibodies, more particularly intended for the prophylaxis of the haemolytic disease of the newborn. The invention also relates to the heterohybridoma cell lines that produce these antibodies, which are filed with the "Deutsche Sammlung von Mikroorganismen und Zellkulturen" under accession numbers DSM AC 2039 and DSM AC 2040.
公开/授权文献
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