Invention Grant
- Patent Title: Quinuclidine derivatives
- Patent Title (中): 奎宁环衍生物
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Application No.: US821500Application Date: 1997-03-21
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Publication No.: US5854256APublication Date: 1998-12-29
- Inventor: John Adams Lowe, III
- Applicant: John Adams Lowe, III
- Applicant Address: NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: NY New York
- Main IPC: A61K31/435
- IPC: A61K31/435 ; A61K31/495 ; A61K31/535 ; A61K31/54 ; A61P1/00 ; A61P25/00 ; A61P25/04 ; A61P29/00 ; C07B59/00 ; C07D453/00 ; C07D453/02 ; C07D471/08 ; C07D471/18 ; C07D491/18 ; C07D495/18 ; C07D498/18 ; C07D513/18 ; A61K31/44 ; C07D221/06 ; C07D221/22
Abstract:
Quinuclidine derivatives of the formula ##STR1## and the pharmaceutically acceptable salts thereof, wherein m, P, Z, Y, R.sup.1, R.sup.2 and R.sup.3 are as defined below. The compounds are substance P antagonists and, therefore, are useful in treating gastrointestinal disorders, central nervous system disorders, inflammatory diseases, pain and migraine.
Public/Granted literature
- US5276432A Patient exit detection mechanism for hospital bed Public/Granted day:1994-01-04
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