发明授权
- 专利标题： Humanized monoclonal antibodies against human interleukin-4
- 专利标题（中）： 针对人白细胞介素-4的人源化单克隆抗体
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申请号： US290793申请日： 1994-08-16
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公开(公告)号： US5863537A公开(公告)日： 1999-01-26
- 发明人: Barbara Dalie , Hung V. Le , Kenneth Miller , Nicholas J. Murgolo , Hanh Nguyen , Stephen Tindall , Paul J. Zavodny
- 申请人： Barbara Dalie , Hung V. Le , Kenneth Miller , Nicholas J. Murgolo , Hanh Nguyen , Stephen Tindall , Paul J. Zavodny
- 申请人地址： NJ Kenilworth
- 专利权人： Schering Corporation
- 当前专利权人： Schering Corporation
- 当前专利权人地址： NJ Kenilworth
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K39/395 ; A61P43/00 ; C07K14/47 ; C07K14/52 ; C07K14/54 ; C07K16/00 ; C07K16/24 ; C07K16/46 ; C12N5/10 ; C12N15/02 ; C12N15/09 ; C12N15/13 ; C12P21/02 ; C12P21/08 ; C12R1/91 ; A61K39/40
摘要：
Monoclonal antibodies are provided which are specific for human interleukin-4. Also provided are complementary DNAs which encode the heavy and light chain variable regions of such monoclonal antibodies and complementarity determining regions from such DNAs; and kits and methods for detecting, measuring and immunopurifying human interleukin-4, and for blocking the biological activity of human interleukin-4.
公开/授权文献
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