发明授权
US5869448A Cyclic CS-1 peptidomimetics, compositions and methods of using same
失效
循环CS-1肽模拟物，组合物和使用方法
- 专利标题： Cyclic CS-1 peptidomimetics, compositions and methods of using same
- 专利标题（中）： 循环CS-1肽模拟物，组合物和使用方法
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申请号： US519109申请日： 1995-08-25
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公开(公告)号： US5869448A公开(公告)日： 1999-02-09
- 发明人: Thomas S. Arrhenius , Anna Tempczyk , Mariano J. Elices , Zhong-Li Zheng
- 申请人： Thomas S. Arrhenius , Anna Tempczyk , Mariano J. Elices , Zhong-Li Zheng
- 申请人地址： CA San Diego
- 专利权人： Cytel Corporation
- 当前专利权人： Cytel Corporation
- 当前专利权人地址： CA San Diego
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; C07K5/083 ; C07K5/103 ; C07K5/117 ; C07K5/12 ; C07K14/78 ; A61K38/08 ; A61K38/12 ; C07K7/00 ; C07K7/56
摘要：
The present invention contemplates a cyclic peptide that inhibits the binding between the VLA-4 receptor expressed on inflammatory leukocytes and the fibronectin CS-1 peptide expressed on endothelial cells that are involved in immunoinflammatory disease states. Pharmaceutical compositions containing a contemplated cyclic peptide and processes for treating immunoinflammatory conditions using a binding-inhibitory cyclic peptide are also disclosed.
公开/授权文献
- US3967654A Yarn feed mechanism for a weaving machine 公开/授权日：1976-07-06
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