Invention Grant
- Patent Title: Pituitary differentiaton factor and methods of use thereof
- Patent Title (中): 垂体分化因子及其使用方法
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Application No.: US977992Application Date: 1997-11-25
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Publication No.: US5888817APublication Date: 1999-03-30
- Inventor: Micsunica Platica , Ovidiu Platica , James F. Holland
- Applicant: Micsunica Platica , Ovidiu Platica , James F. Holland
- Applicant Address: NY New York
- Assignee: The Mount Sinai School of Medicine
- Current Assignee: The Mount Sinai School of Medicine
- Current Assignee Address: NY New York
- Main IPC: C12N15/09
- IPC: C12N15/09 ; A61K38/00 ; A61K38/22 ; A61P35/00 ; C07K14/47 ; C07K14/575 ; C12N1/15 ; C12N1/19 ; C12N1/21 ; C12N5/10 ; C12P21/02 ; C12N5/00 ; C12P21/04
Abstract:
The present invention is directed to pituitary differentiation factor (PDF), a pituitary factor that is capable of differentiating cells including breast cancer and prostatic cancer cells. Isolated nucleic acids encoding PDF and related vectors and host cells are also provided. Restoration of differentiating ability to malignantly transformed cells provides a modality of cancer therapy. The isolated and purified PDF of the invention is accordingly useful in the treatment of breast and prostatic cancer.
Public/Granted literature
- US5320007A Method for positioning and processing LPE films Public/Granted day:1994-06-14
Information query
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