发明授权
- 专利标题: Therapeutic uses of keratinocyte growth factor
- 专利标题(中): 角质形成细胞生长因子的治疗用途
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申请号: US484068申请日: 1995-06-06
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公开(公告)号: US5965530A公开(公告)日: 1999-10-12
- 发明人: Glenn Francis Pierce , Regina Mae Housley , Charles Frederick Morris
- 申请人: Glenn Francis Pierce , Regina Mae Housley , Charles Frederick Morris
- 申请人地址: CA Thousand Oaks
- 专利权人: Amgen Inc.
- 当前专利权人: Amgen Inc.
- 当前专利权人地址: CA Thousand Oaks
- 主分类号: A61K38/00
- IPC分类号: A61K38/00 ; A61K38/18 ; C07K14/50 ; C12N5/071 ; C12N15/00 ; C12N5/00
摘要:
Based on extensive in vivo studies in animals, it has now been discovered that KGF stimulates proliferation, growth and differentiation in various cells of epithelial tissue, besides keratinocytes. This better understanding of the biological effects of KGF in vivo enables the use of this polypeptide as a therapeutic agent, suitably formulated in a pharmaceutical composition, for the specific treatment of disease states and medical conditions afflicting tissues and organs such as the dermal adnexae, the liver, the lung, and the gastrointestinal tract.
公开/授权文献
- US4522542A Apparatus for producing finished booklets 公开/授权日:1985-06-11
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