发明授权
US5976841A Proteins having fibrinolytic and coagulation--inhibiting properties
失效
具有纤维蛋白溶解和凝固抑制性质的蛋白质
- 专利标题: Proteins having fibrinolytic and coagulation--inhibiting properties
- 专利标题(中): 具有纤维蛋白溶解和凝固抑制性质的蛋白质
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申请号: US560098申请日: 1995-11-17
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公开(公告)号: US5976841A公开(公告)日: 1999-11-02
- 发明人: Stephan Wnendt , Regina Heinzel-Wieland , Gerd Josef Steffens
- 申请人: Stephan Wnendt , Regina Heinzel-Wieland , Gerd Josef Steffens
- 申请人地址: DEX Aachen
- 专利权人: Gruenenthal GmbH
- 当前专利权人: Gruenenthal GmbH
- 当前专利权人地址: DEX Aachen
- 优先权: DEX4440892 19941117
- 主分类号: C12N15/09
- IPC分类号: C12N15/09 ; A61K38/00 ; A61K38/46 ; A61P7/02 ; C07K14/475 ; C07K14/815 ; C07K19/00 ; C12N9/64 ; C12N9/72 ; C12N15/58 ; C12P21/02 ; C12R1/19 ; C12N15/62 ; A61K37/00
摘要:
Proteins having fibrinolytic and coagulation-inhibiting properties which are linked at the N- and/or C-terminal end of the plasminogen-activating amino acid sequence to a thrombin- or factor Xa-inhibiting amino acid sequence. The proteins, which are produced by genetic engineering, are useful as thrombolytic agents.
公开/授权文献
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