- 专利标题： Benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
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申请号： US109551申请日： 1998-07-02
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公开(公告)号： US5994391A公开(公告)日： 1999-11-30
- 发明人: Len F. Lee , Shyamal C. Banerjee , Horng-Chih Huang , Jinglin J. Li , Raymond E. Miller , David B. Reitz , Samuel J. Tremont
- 申请人： Len F. Lee , Shyamal C. Banerjee , Horng-Chih Huang , Jinglin J. Li , Raymond E. Miller , David B. Reitz , Samuel J. Tremont
- 申请人地址： IL Skokie
- 专利权人： G.D. Searle and Company
- 当前专利权人： G.D. Searle and Company
- 当前专利权人地址： IL Skokie
- 主分类号： A61K31/00
- IPC分类号： A61K31/00 ; A61K31/38 ; A61K31/4035 ; A61K31/41 ; A61K31/4178 ; A61K31/4433 ; A61K31/4436 ; A61K31/4709 ; A61K31/4995 ; A61K31/662 ; A61K31/67 ; A61P1/16 ; A61P3/06 ; A61P9/10 ; A61P43/00 ; C07B53/00 ; C07C319/14 ; C07C323/12 ; C07C323/18 ; C07C323/19 ; C07D337/06 ; C07D337/08 ; C07D409/10 ; C07D409/12 ; C07D487/08 ; C07D495/04 ; C07D495/10 ; C07F9/653 ; C07F9/6553 ; C07K5/06 ; C07K5/068 ; C08G65/329 ; A61K31/44 ; C07D211/72 ; C07D337/00
摘要：
Provided are novel benzothiepines, derivatives, and analogs thereof; pharmaceutical compositions containing them; and methods of using these compounds and compositions in medicine, particularly in the prophylaxis and treatment of hyperlipidemic conditions such as those associated with atherosclerosis or hypercholesterolemia, in mammals.
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