- 专利标题： Aromatic heterocyclic compounds and their use as anti-inflammatory agents
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申请号： US181743申请日： 1998-10-29
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公开(公告)号： US6080763A公开(公告)日： 2000-06-27
- 发明人: John R. Regan , Pier F. Cirillo , Eugene R. Hickey , Neil Moss , Charles L. Cywin , Christopher Pargellis , Thomas A. Gilmore
- 申请人： John R. Regan , Pier F. Cirillo , Eugene R. Hickey , Neil Moss , Charles L. Cywin , Christopher Pargellis , Thomas A. Gilmore
- 申请人地址： CT Ridgefield
- 专利权人： Boehringer Ingelheim Pharmaceuticals, Inc.
- 当前专利权人： Boehringer Ingelheim Pharmaceuticals, Inc.
- 当前专利权人地址： CT Ridgefield
- 主分类号： A61K31/381
- IPC分类号： A61K31/381 ; A61K31/415 ; A61K31/4184 ; A61K31/4427 ; A61K31/443 ; A61K31/4433 ; A61K31/4436 ; A61K31/4439 ; A61K31/4725 ; A61P29/00 ; C07D231/40 ; C07D235/30 ; C07D333/36 ; C07D401/04 ; C07D401/12 ; C07D405/12 ; C07D409/04 ; A61K31/44 ; C07D231/38
摘要：
Novel aromatic heterocyclic compounds inhibit cytokines production involved in immunoregulation and inflammation such as interleukin-1 and tumor necrosis factor production. The compounds are therefore useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic inflammatory diseases.
公开/授权文献
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