发明授权
- 专利标题: Cloning and expression of .beta.APP-C100 receptor (C100-R)
- 专利标题(中): βAPP-C100受体(C100-R)的克隆和表达
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申请号: US559397申请日: 1995-11-15
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公开(公告)号: US6083713A公开(公告)日: 2000-07-04
- 发明人: Susan P. Manly , Michael R. Kozlowski , Rachael L. Neve
- 申请人: Susan P. Manly , Michael R. Kozlowski , Rachael L. Neve
- 申请人地址: NY New York MA Belmont
- 专利权人: Bristol-Myers Squibb Company,McLean Hospital Corporation
- 当前专利权人: Bristol-Myers Squibb Company,McLean Hospital Corporation
- 当前专利权人地址: NY New York MA Belmont
- 主分类号: G01N33/53
- IPC分类号: G01N33/53 ; A61K31/00 ; A61K31/70 ; A61K31/7088 ; A61K38/00 ; A61K39/395 ; A61P25/28 ; C07K14/47 ; C07K14/705 ; C07K16/28 ; C07K19/00 ; C12N1/21 ; C12N5/10 ; C12N15/00 ; C12N15/09 ; C12N15/113 ; C12N15/12 ; C12P21/02 ; C12P21/08 ; C12Q1/68 ; C12R1/91 ; G01N33/566 ; G01N33/577 ; G01N33/68 ; C12N15/70 ; C12N15/85
摘要:
The present invention relates to the cloning of .beta.APP-C100 receptor (C100-R), and genetically engineered host cells which express the C100-R. Such engineered cells may be used to evaluate and screen drugs and analogs of .beta.-APP involved in Alzheimer's Disease.
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