Invention Grant
US6087304A Substituted 2-naphthoylguanidines, process for their preparation, their
use as a medicament or diagnostic, and medicament containing them
失效
取代的2-萘酰基胍，其制备方法，它们作为药物或诊断剂的用途，以及含有它们的药物
- Patent Title: Substituted 2-naphthoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them
- Patent Title (中): 取代的2-萘酰基胍，其制备方法，它们作为药物或诊断剂的用途，以及含有它们的药物
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Application No.: US857631Application Date: 1997-05-16
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Publication No.: US6087304APublication Date: 2000-07-11
- Inventor: Joachim Brendel , Heinz-Werner Kleemann , Heinrich Christian Englert , Hans Jochen Lang , Jan-Robert Schwark , Andreas Weichert , Bansi Lal
- Applicant: Joachim Brendel , Heinz-Werner Kleemann , Heinrich Christian Englert , Hans Jochen Lang , Jan-Robert Schwark , Andreas Weichert , Bansi Lal
- Applicant Address: DEX Frankfurt am Main
- Assignee: Hoechst Aktiengesellschaft
- Current Assignee: Hoechst Aktiengesellschaft
- Current Assignee Address: DEX Frankfurt am Main
- Priority: DEX19621483 19960529
- Main IPC: C07D295/14
- IPC: C07D295/14 ; A01N1/02 ; A01N47/44 ; A61K31/155 ; A61K31/165 ; A61K31/27 ; A61K31/44 ; A61K31/495 ; A61K31/535 ; A61K31/5375 ; A61P3/06 ; A61P9/00 ; A61P9/06 ; A61P9/10 ; A61P35/00 ; A61P43/00 ; C07C271/22 ; C07C277/08 ; C07C279/20 ; C07C279/22 ; C07C311/19 ; C07C317/50 ; C07C323/62 ; C07D213/40 ; C07D213/75 ; C07D295/08 ; C07D295/088 ; A01N37/10 ; C07D211/70 ; C07D241/04 ; C07D265/30
Abstract:
Substituted 2-naphthoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing themSubstituted 2-naphthoylguanidines of the formula I ##STR1## having the meanings indicated in claim 1 for R1 to R8, are suitable as antiarrhythmic pharmaceuticals having a cardioprotective component for infarct prophylaxis and infarct treatment and for the treatment of angina pectoris. They also preventively inhibit the pathophysiological processes in the formation of ischemically induced damage, in particular in the production of ischemically induced cardiac arrhythmias.
Public/Granted literature
- US5328655A Method and apparatus for the manufacture of shaped products of biaxially oriented polymeric material Public/Granted day:1994-07-12
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