Invention Grant
US6103719A Neurokinin antagonists, processes for preparing them and pharmaceutical
compositions containing these compounds
失效
神经激肽拮抗剂，其制备方法和含有这些化合物的药物组合物
- Patent Title: Neurokinin antagonists, processes for preparing them and pharmaceutical compositions containing these compounds
- Patent Title (中): 神经激肽拮抗剂，其制备方法和含有这些化合物的药物组合物
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Application No.: US320974Application Date: 1999-05-27
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Publication No.: US6103719APublication Date: 2000-08-15
- Inventor: Franz Esser , Gerd Schnorrenberg , Horst Dollinger , Sven Luettke , Birgit Jung , Georg Speck
- Applicant: Franz Esser , Gerd Schnorrenberg , Horst Dollinger , Sven Luettke , Birgit Jung , Georg Speck
- Applicant Address: DEX Ingelheim am Rhein
- Assignee: Boehringer Ingelheim Pharma KG
- Current Assignee: Boehringer Ingelheim Pharma KG
- Current Assignee Address: DEX Ingelheim am Rhein
- Priority: DEX19824470 19980530
- Main IPC: C07D295/14
- IPC: C07D295/14 ; A61K31/4427 ; A61K31/4468 ; A61K31/4545 ; A61K31/495 ; A61K31/496 ; A61K31/5375 ; A61K31/5377 ; A61P43/00 ; C07D211/58 ; C07D233/44 ; C07D233/46 ; C07D233/48 ; C07D233/54 ; C07D239/12 ; C07D295/215 ; C07D401/12 ; C07D295/125 ; C07D401/06 ; C07D403/06 ; C07D413/06
Abstract:
The invention relates to new compounds of general formula I ##STR1## or the pharmaceutically acceptable salts thereof, wherein X=N--R.sup.3 or CH--R.sup.4,Y=CH.sub.2 or (CH.sub.2).sub.2,Z=O or H.sub.2 ;and R.sup.1, R.sup.2, R.sup.3, R.sup.4 and Ar have the meanings given in the specification, and the preparation and use thereof. The new compounds are valuable neurokinin (tachykinin) antagonists.
Public/Granted literature
- US4922065A Temperature-compensating accelerometer Public/Granted day:1990-05-01
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