发明授权
- 专利标题: Fractional cell sorter
- 专利标题(中): 分数细胞分选机
-
申请号: US352725申请日: 1999-07-13
-
公开(公告)号: US6120735A公开(公告)日: 2000-09-19
- 发明人: Maciej Zborowski , Jeff Chalmers , Lee R. Moore
- 申请人: Maciej Zborowski , Jeff Chalmers , Lee R. Moore
- 申请人地址: OH Columbus OH Cleveland
- 专利权人: The Ohio States University,The Cleveland Clinic Foundation
- 当前专利权人: The Ohio States University,The Cleveland Clinic Foundation
- 当前专利权人地址: OH Columbus OH Cleveland
- 主分类号: G01N15/14
- IPC分类号: G01N15/14 ; G01N33/49 ; G01N33/00
摘要:
A method and apparatus for the fraction sorting of cells is provided. The invention include a dispensing device, aspirating device, flow channel and a magnetic assembly. A first fractional sorting device includes a dipole fractional cell sorter. The dipole fractional cell sorter includes large aspect ratio flow channel and a dipole magnetic assembly. A second fractional sorting device includes a quadrupole fractional cell sorter. The quadrupole fractional cell sorter includes an annular flow channel having inlet and outlet splitters, and a quadrupole magnetic assembly. The quadrupole magnetic assembly includes pole pieces having projecting members with convex surfaces and in is in physical communication with the annular flow chamber. The method of the present invention provides a flow through fractional cell sorting process which is based on the application of a magnetic force to cells having a range of magnetic labeling densities.
公开/授权文献
- US5615461A Fastening device 公开/授权日:1997-04-01
信息查询