发明授权
- 专利标题： Isolation and production of a cyclophilin-like protein endogenous to brugia malayi
- 专利标题（中）： 分离和产生马齿苋的内源性亲环蛋白样蛋白
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申请号： US134852申请日： 1998-08-14
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公开(公告)号： US6127148A公开(公告)日： 2000-10-03
- 发明人: Clotilde K. S. Carlow , Antony Page
- 申请人： Clotilde K. S. Carlow , Antony Page
- 申请人地址： MA Beverly
- 专利权人： New England Biolabs, Inc.
- 当前专利权人： New England Biolabs, Inc.
- 当前专利权人地址： MA Beverly
- 主分类号： G01N33/566
- IPC分类号： G01N33/566 ; C07H21/04 ; C07K1/22 ; C07K14/435 ; C07K14/44 ; C12N15/09 ; C12P21/02 ; C12P21/06 ; C12N1/00 ; C12N1/20
摘要：
The present invention relates to the use of nematode "cyclophilin-like proteins (CLP)", in a method for identifying compounds capable of binding to and/or inhibiting the peptidyl-prolylcistransisomerase activity of these proteins. Such compounds may be further screened for their ability to inhibit nematode parasites which are not susceptible to the anti-parasitic effects of CsA.
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