发明授权
US6136527A Polypeptides derived from proteins of the hepatitis C virus, test kits
containing these polypeptides and vaccines against infections of
hepatitis C viruses
失效
衍生自丙型肝炎病毒蛋白质的多肽,含有这些多肽的试剂盒和针对丙型肝炎病毒感染的疫苗
- 专利标题: Polypeptides derived from proteins of the hepatitis C virus, test kits containing these polypeptides and vaccines against infections of hepatitis C viruses
- 专利标题(中): 衍生自丙型肝炎病毒蛋白质的多肽,含有这些多肽的试剂盒和针对丙型肝炎病毒感染的疫苗
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申请号: US78271申请日: 1993-10-15
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公开(公告)号: US6136527A公开(公告)日: 2000-10-24
- 发明人: Klaus Fuchs , Manfred Motz , Michael Roggendorf , Erwin Soutschek
- 申请人: Klaus Fuchs , Manfred Motz , Michael Roggendorf , Erwin Soutschek
- 申请人地址: DEX Mannheim
- 专利权人: Roche Diagnostics GmbH
- 当前专利权人: Roche Diagnostics GmbH
- 当前专利权人地址: DEX Mannheim
- 优先权: DEX4041304 19901221
- 主分类号: A61K39/29
- IPC分类号: A61K39/29 ; A61K39/00 ; A61P31/12 ; C07H21/04 ; C07K14/00 ; C07K14/02 ; C07K14/10 ; C07K14/18 ; C07K14/705 ; C07K19/00 ; C12N1/21 ; C12N15/09 ; C12N15/51 ; C12P21/02 ; C12Q1/68 ; C12R1/19 ; G01N33/53 ; G01N33/576
摘要:
The cloning and sequencing of different polypeptides from the genome of a hepatitis C virus is disclosed. The polypeptides are prepared as non-fusion proteins in good yield. The polypeptide originating from the structure protein (core) is soluble under physiological conditions. Since the polypeptides have no foreign protein portions, they are preferably used in test kits and as vaccine.
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