发明授权
US6140322A Amidine and isothiourea derivatives as inhibitors of nitric oxide
synthase
失效
脒和异硫脲衍生物作为一氧化氮合酶的抑制剂
- 专利标题: Amidine and isothiourea derivatives as inhibitors of nitric oxide synthase
- 专利标题(中): 脒和异硫脲衍生物作为一氧化氮合酶的抑制剂
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申请号: US233476申请日: 1999-01-20
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公开(公告)号: US6140322A公开(公告)日: 2000-10-31
- 发明人: James MacDonald , James Matz , William Shakespeare
- 申请人: James MacDonald , James Matz , William Shakespeare
- 申请人地址: SEX Sodertalje
- 专利权人: Astra Aktiebolag
- 当前专利权人: Astra Aktiebolag
- 当前专利权人地址: SEX Sodertalje
- 优先权: SEX9600275 19960125; SEX9603300 19960911; SEX9603301 19960911
- 主分类号: C07D409/12
- IPC分类号: C07D409/12 ; C07D413/12 ; C07D413/14 ; C07D471/04 ; C07D487/04 ; C07D498/04 ; A61K31/445 ; C07D489/04
摘要:
There are provided novel compounds of formula (I) ##STR1## wherein X, R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are as defined in the specification and optical isomers and racemates thereof and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy.
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