- 专利标题: Hybrid proteins with modified activity
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申请号: US324934申请日: 1999-06-03
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公开(公告)号: US6156888A公开(公告)日: 2000-12-05
- 发明人: Johannes J. Voorberg
- 申请人: Johannes J. Voorberg
- 申请人地址: ATX Vienna
- 专利权人: Baxter Aktiengesellschaft
- 当前专利权人: Baxter Aktiengesellschaft
- 当前专利权人地址: ATX Vienna
- 主分类号: G01N33/68
- IPC分类号: G01N33/68 ; A61K38/00 ; A61K38/43 ; A61K38/55 ; C07K14/755 ; C07K14/81 ; C07K14/815 ; C07K16/36 ; C07K19/00 ; C12N5/10 ; C12N15/02 ; C12N15/09 ; C12P21/08 ; G01N33/86 ; C07H21/02 ; A01N43/04 ; C07H21/04
摘要:
Hybrid proteins which affect blood coagulation comprise a region from a donor anticoagulant or antithrombotic protein, and the resulting hybrid protein has a modified biological activity. Information concerning the hybrid proteins implicates DNA sequences encoding the proteins and hosts, including transgenic animals, that possess these DNA sequences; antibodies directed against hybrid proteins; methods of modifying the properties of proteins; and treatment methods employing hybrid proteins.
公开/授权文献
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