- 专利标题： Streptococcus pneumoniae antigens and vaccines
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申请号： US961083申请日： 1997-10-30
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公开(公告)号： US6159469A公开(公告)日： 2000-12-12
- 发明人: Gil H. Choi , Charles A. Kunsch , Steven C. Barash , Patrick J. Dillon , Brian Dougherty , Michael R. Fannon , Craig A. Rosen
- 申请人： Gil H. Choi , Charles A. Kunsch , Steven C. Barash , Patrick J. Dillon , Brian Dougherty , Michael R. Fannon , Craig A. Rosen
- 申请人地址： MD Rockville
- 专利权人： Human Genome Sciences, Inc.
- 当前专利权人： Human Genome Sciences, Inc.
- 当前专利权人地址： MD Rockville
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; A01K67/027 ; A61K38/00 ; A61K39/00 ; A61K39/09 ; A61K48/00 ; A61P31/04 ; C07K14/315 ; C07K16/12 ; C12N1/15 ; C12N1/19 ; C12N1/21 ; C12N5/00 ; C12N5/10 ; C12N5/18 ; C12N15/09 ; C12N15/31 ; C12P21/02 ; C12Q1/68 ; G01N33/50 ; G01N33/569 ; G06F17/30 ; A61K39/40 ; A61K39/02 ; A61K39/385
摘要：
The present invention relates to novel vaccines for the prevention or attenuation of infection by Streptococcus pneumoniae. The invention further relates to isolated nucleic acid molecules encoding antigenic polypeptides of Streptococcus pneumoniae. Antigenic polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. The invention additionally relates to diagnostic methods for detecting Streptococcus nucleic acids, polypeptides and antibodies in a biological sample.