发明授权
US06166197A Oligomeric compounds having pyrimidine nucleotide (S) with 2'and 5
substitutions
失效
具有嘧啶核苷酸(S)的具有2'-5个取代基的低聚化合物
- 专利标题: Oligomeric compounds having pyrimidine nucleotide (S) with 2'and 5 substitutions
- 专利标题(中): 具有嘧啶核苷酸(S)的具有2'-5个取代基的低聚化合物
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申请号: US398901申请日: 1995-03-06
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公开(公告)号: US06166197A公开(公告)日: 2000-12-26
- 发明人: Phillip Dan Cook , Yogesh S. Sanghvi , Kelly G. Sprankle , Bruce S. Ross , Rich H. Griffey
- 申请人: Phillip Dan Cook , Yogesh S. Sanghvi , Kelly G. Sprankle , Bruce S. Ross , Rich H. Griffey
- 申请人地址: CA Carlsbad
- 专利权人: ISIS Pharmaceuticals, Inc.
- 当前专利权人: ISIS Pharmaceuticals, Inc.
- 当前专利权人地址: CA Carlsbad
- 主分类号: C07H19/06
- IPC分类号: C07H19/06 ; C07H21/00 ; C07H19/00 ; C07H21/02 ; C07H21/04
摘要:
Oligonucleotide analogs are disclosed having pyrimidine monomeric sub-units therein that are modified at the 2' and 5 positions. Monomeric sub-units having these modifications may be further modified at the 2 position.
公开/授权文献
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