发明授权
- 专利标题： 3′-exonuclease, production and use thereof
- 专利标题（中）： 3'-外切核酸酶，其生产和使用
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申请号： US09719787申请日： 2000-12-15
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公开(公告)号： US06451307B1公开(公告)日： 2002-09-17
- 发明人: Thomas Neumann , Christoph Hüls , Karl-Christian Gallert , Anders Virtanen , Jonas Aström , Javier Martinez , Ann-Charlotte Thuresson , Yanguo Ren
- 申请人： Thomas Neumann , Christoph Hüls , Karl-Christian Gallert , Anders Virtanen , Jonas Aström , Javier Martinez , Ann-Charlotte Thuresson , Yanguo Ren
- 优先权： DE19828711 19980629
- 主分类号： A61K3846
- IPC分类号： A61K3846
摘要：
The present invention relates to a poly(A)-specific 3′-exonuclease activity which can be obtained by chromatographically purifying a crude extract of animal or human cells and to its use for deadenylating 3′-poly(A) tails of nucleic acids and as a pharmaceutical or diagnostic agent, or for identifying functional interactors.
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