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公开(公告)号:US06579681B1
公开(公告)日:2003-06-17
申请号:US09857063
申请日:2001-11-27
申请人: Christoph Hüls , Bettina Bauer , Claus Simandi , Reinhard Lührmann , Tilmann Achsel , Hans-Peter Vornlocher
发明人: Christoph Hüls , Bettina Bauer , Claus Simandi , Reinhard Lührmann , Tilmann Achsel , Hans-Peter Vornlocher
IPC分类号: C12Q168
CPC分类号: G01N33/5308 , C12Q1/6883
摘要: The present invention relates to a test system comprising (a) one or more identical or different immobilized nucleic acid(s) having at least one spliceable nucleic acid, (b) at least one gel-free detection system for detecting a splicing reaction, where appropriate (c) at least one composition comprising splicing components, and preferably (d) suitable detection probes, and, where appropriate, (e) further aids.
摘要翻译: 本发明涉及包含(a)一种或多种相同或不同的具有至少一个可剪接核酸的固定化核酸的测试系统,(b)至少一种用于检测剪接反应的无凝胶检测系统,其中 (c)至少一种组合物,其包含剪接组分,优选(d)合适的检测探针,以及在适当的情况下,(e)进一步的辅助剂。
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公开(公告)号:US06451307B1
公开(公告)日:2002-09-17
申请号:US09719787
申请日:2000-12-15
申请人: Thomas Neumann , Christoph Hüls , Karl-Christian Gallert , Anders Virtanen , Jonas Aström , Javier Martinez , Ann-Charlotte Thuresson , Yanguo Ren
发明人: Thomas Neumann , Christoph Hüls , Karl-Christian Gallert , Anders Virtanen , Jonas Aström , Javier Martinez , Ann-Charlotte Thuresson , Yanguo Ren
IPC分类号: A61K3846
摘要: The present invention relates to a poly(A)-specific 3′-exonuclease activity which can be obtained by chromatographically purifying a crude extract of animal or human cells and to its use for deadenylating 3′-poly(A) tails of nucleic acids and as a pharmaceutical or diagnostic agent, or for identifying functional interactors.
摘要翻译: 本发明涉及通过色谱纯化动物或人细胞的粗提取物而获得的聚(A)特异性3'-外切核酸酶活性,并且其用于使核酸的3'-聚(A)尾部残基烯化, 作为药物或诊断剂,或用于鉴定功能性交互作用。
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公开(公告)号:US06582691B1
公开(公告)日:2003-06-24
申请号:US09601537
申请日:2000-09-29
IPC分类号: A61K4800
CPC分类号: C12N15/86 , C07K2319/00 , C12N9/90 , C12N2710/14143
摘要: The invention relates to an insect cell vector for the production of proteins from the DEAD protein family.
摘要翻译: 本发明涉及用于从DEAD蛋白家族生产蛋白质的昆虫细胞载体。
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