Invention Grant
- Patent Title: HPV-specific oligonucleotides
- Patent Title (中): HPV特异性寡核苷酸
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Application No.: US08887497Application Date: 1997-07-02
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Publication No.: US06458940B2Publication Date: 2002-10-01
- Inventor: Peter C. Roberts , Bruce L. Frank , David E. Szymkowski , John S. Mills , John Goodchild , Jia L. Wolfe , Robert E. Kilkuskie , Isobel M. Greenfield , Veronica Sullivan
- Applicant: Peter C. Roberts , Bruce L. Frank , David E. Szymkowski , John S. Mills , John Goodchild , Jia L. Wolfe , Robert E. Kilkuskie , Isobel M. Greenfield , Veronica Sullivan
- Main IPC: C07H2102
- IPC: C07H2102
Abstract:
The present invention discloses synthetic oligonucleotides complementary to a nucleic acid spanning the translational start site of human papillomavirus gene E1, and including at least 15 nucleotides. Also disclosed are methods and kits for inhibiting the replication of HPV, for inhibiting the expression of HPV nucleic acid and protein, for detection of HPV, and for treating HPV infections.
Public/Granted literature
- US20010010899A1 HPV-SPECIFIC OLIGONUCLEOTIDES Public/Granted day:2001-08-02
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