Invention Grant
- Patent Title: IL-17 related mammalian cytokine polypeptides (IL-17E)
- Patent Title (中): IL-17相关哺乳动物细胞因子多肽(IL-17E)
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Application No.: US09816744Application Date: 2001-03-22
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Publication No.: US06579520B2Publication Date: 2003-06-17
- Inventor: Jian Chen , Ellen Filvaroff , Sherman Fong , Audrey Goddard , Paul Godowski , Christopher Grimaldi , Austin Gurney , Hanzhong Li , Kenneth Hillan , Daniel Tumas , Menno VanLookeren , Richard Vandlen , Colin Watanabe , P. Mickey Williams , William I. Wood , Daniel Yansura
- Applicant: Jian Chen , Ellen Filvaroff , Sherman Fong , Audrey Goddard , Paul Godowski , Christopher Grimaldi , Austin Gurney , Hanzhong Li , Kenneth Hillan , Daniel Tumas , Menno VanLookeren , Richard Vandlen , Colin Watanabe , P. Mickey Williams , William I. Wood , Daniel Yansura
- Main IPC: A61K4505
- IPC: A61K4505

Abstract:
The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.
Public/Granted literature
- US20030003546A1 lL-17 homologous polypeptides and therapeutic uses thereof Public/Granted day:2003-01-02
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