发明授权
US06855528B2 Methods for identifying inducers and inhibitors of proteolytic antibodies, compositions and their uses
有权
用于鉴定诱导物和蛋白水解抗体抑制剂的方法，组合物及其用途
- 专利标题： Methods for identifying inducers and inhibitors of proteolytic antibodies, compositions and their uses
- 专利标题（中）： 用于鉴定诱导物和蛋白水解抗体抑制剂的方法，组合物及其用途
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申请号： US09862849申请日： 2001-05-22
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公开(公告)号： US06855528B2公开(公告)日： 2005-02-15
- 发明人: Sudhir Paul , Gennady Gololobov , Larry J. Smith
- 申请人： Sudhir Paul , Gennady Gololobov , Larry J. Smith
- 申请人地址： US NE Omaha US NE Lincoln
- 专利权人： Larry J. Smith,University of Nebraska Board of Regents
- 当前专利权人： Larry J. Smith,University of Nebraska Board of Regents
- 当前专利权人地址： US NE Omaha US NE Lincoln
- 代理机构： Dann, Dorfman, Herrell and Skillman
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K38/00 ; A61K39/395 ; A61P5/14 ; A61P11/06 ; A61P17/00 ; A61P19/02 ; A61P19/04 ; A61P29/00 ; A61P35/00 ; A61P37/06 ; C07K7/04 ; C07K16/00 ; C07K16/10 ; C07K16/32 ; C12N9/00 ; C12N9/64 ; A61K38/04 ; A61K38/43
摘要：
Covalently reactive antigen analogs are disclosed herein. The antigens of the invention may be used to stimulate production of catalytic antibodies specific for predetermined antigens assocated with particular medical disorders. The antigen analogs may also be used to permanently inactivate endogenously produced catalytic antibodies produced in certain autoimmune diseases as well as in certain lymphoproliferative disorders.
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