发明授权
- 专利标题： Pyridine and pyrimidine derivatives
- 专利标题（中）： 吡啶和嘧啶衍生物
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申请号： US10361268申请日： 2003-02-10
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公开(公告)号： US06867205B2公开(公告)日： 2005-03-15
- 发明人: Markus Boehringer , Bernd Michael Loeffler , Jens-Uwe Peters , Matthias Steger , Peter Weiss
- 申请人： Markus Boehringer , Bernd Michael Loeffler , Jens-Uwe Peters , Matthias Steger , Peter Weiss
- 申请人地址： US NJ Nutley
- 专利权人： Hoffman-La Roche Inc.
- 当前专利权人： Hoffman-La Roche Inc.
- 当前专利权人地址： US NJ Nutley
- 代理商 George W. Johnston; Dennis P. Tramaloni; Samuel H. Megerditchian
- 优先权： EP02003114 20020213
- 主分类号： A61K31/4418
- IPC分类号： A61K31/4418 ; A61K31/443 ; A61K31/505 ; A61K31/506 ; A61K31/5377 ; A61P1/04 ; A61P3/00 ; A61P3/04 ; A61P3/10 ; A61P7/10 ; A61P9/12 ; C07D213/73 ; C07D239/42 ; C07D401/04 ; C07D403/04 ; C07D405/04 ; C07D409/04
摘要：
The present invention provides compounds of formula (I) wherein R1, R2, R3, R4 and X are as defined in the specification, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP IV, such as diabetes, particularly non-insulin dependent diabetes mellitus, and impaired glucose tolerance.
公开/授权文献
- US20030216382A1 Pyridine and pyrimidine derivatives 公开/授权日：2003-11-20
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