发明授权
US06888022B2 Methods and compounds for inhibiting β-amyloid peptide release and/or its synthesis
失效
用于抑制β-淀粉样蛋白肽释放和/或其合成的方法和化合物
- 专利标题： Methods and compounds for inhibiting β-amyloid peptide release and/or its synthesis
- 专利标题（中）： 用于抑制β-淀粉样蛋白肽释放和/或其合成的方法和化合物
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申请号： US09789487申请日： 2001-02-20
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公开(公告)号： US06888022B2公开(公告)日： 2005-05-03
- 发明人: James E. Audia , Thomas C. Britton , James J. Droste , Beverly K. Folmer , George W. Huffman , Varghese John , Lee H. Latimer , Thomas E. Mabry , Jeffrey S. Nissen , Warren J. Porter , Jon K. Reel , Eugene D. Thorsett , Jay S. Tung , Jing Wu , Clark Norman Eid , William Leonard Scott
- 申请人： James E. Audia , Thomas C. Britton , James J. Droste , Beverly K. Folmer , George W. Huffman , Varghese John , Lee H. Latimer , Thomas E. Mabry , Jeffrey S. Nissen , Warren J. Porter , Jon K. Reel , Eugene D. Thorsett , Jay S. Tung , Jing Wu , Clark Norman Eid , William Leonard Scott
- 申请人地址： US CA S. San Francisco US IN Indianapolis
- 专利权人： Athena Neurosciences, Inc.,Eli Lilly & Company
- 当前专利权人： Athena Neurosciences, Inc.,Eli Lilly & Company
- 当前专利权人地址： US CA S. San Francisco US IN Indianapolis
- 代理机构： Burns, Doane, Swecker & Mathis, LLP
- 主分类号： A61K31/00
- IPC分类号： A61K31/00 ; A61K38/05 ; A61K38/06 ; C07K5/06 ; C07K5/065 ; C07C229/00
摘要：
Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.