发明授权
- 专利标题: Aryl and heteroaryl sulfonates
- 专利标题(中): 芳基和杂芳基磺酸盐
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申请号: US10240464申请日: 2001-03-19
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公开(公告)号: US06919470B2公开(公告)日: 2005-07-19
- 发明人: Markus Heil , Heinrich Meier , Paul Naab , Arnd Voerste , Jean-Marie-Viktor de Vry , Dirk Denzer , Frank Mauler , Klemens Lustig , Volker Hinz , Swen Allerheiligen
- 申请人: Markus Heil , Heinrich Meier , Paul Naab , Arnd Voerste , Jean-Marie-Viktor de Vry , Dirk Denzer , Frank Mauler , Klemens Lustig , Volker Hinz , Swen Allerheiligen
- 申请人地址: DE Leverkusen
- 专利权人: Bayer Aktiengesellschaft
- 当前专利权人: Bayer Aktiengesellschaft
- 当前专利权人地址: DE Leverkusen
- 代理商 Susan M. Pellegrino
- 优先权: DE10015866 20000330
- 国际申请: PCT/EP01/03119 WO 20010319
- 国际公布: WO01/74763 WO 20011011
- 主分类号: C07D317/54
- IPC分类号: C07D317/54 ; A61K31/255 ; A61K31/343 ; A61K31/36 ; A61K31/415 ; A61K31/416 ; A61K31/421 ; A61K31/423 ; A61K31/426 ; A61K31/44 ; A61K31/443 ; A61K31/47 ; A61K31/4704 ; A61P1/08 ; A61P11/06 ; A61P13/12 ; A61P21/00 ; A61P25/00 ; A61P25/04 ; A61P25/06 ; A61P25/08 ; A61P25/14 ; A61P25/16 ; A61P25/26 ; A61P25/28 ; A61P27/06 ; A61P29/00 ; A61P37/02 ; A61P37/08 ; A61P43/00 ; C07B61/00 ; C07C303/28 ; C07C309/65 ; C07D213/30 ; C07D213/68 ; C07D215/02 ; C07D215/14 ; C07D217/02 ; C07D217/16 ; C07D231/12 ; C07D231/56 ; C07D261/20 ; C07D263/32 ; C07D263/56 ; C07D277/24 ; C07D307/79 ; C07D307/82 ; C07D317/46 ; C07D405/04 ; C07C309/63
摘要:
The invention relates to novel aryl and heteroaryl sulfonates of formula (Ia) and to methods for producing them and to novel aryl and heteroaryl sulfonates of formula (I) for treating and/or preventing diseases, especially for treating pain and neurodegenerative diseases, A representing (C6-C10)-aryl or 5-10-membered heteroaryl, D representing (C6-C10)-arylene or 5-10-membered heteroarylene, R1 representing (C4-C8)-alkyl, (C2-C8)-alkyl, the carbon chain being interrupted by one or two heteroatoms or groups chosen from the following group: —O—, —S—, —SO— and —SO2—, (C2-C8)-alkenyl or (C2-C8)-alkinyl, in formula (Ia); and R1 representing (C3-C8)-alkyl, (C2-C8)-alkyl, the carbon chain being interrupted by one or two heteroatoms or groups chosen from the following group: —O—, —S—,—SO— and —SO2—, (C2-C8)-alkenyl or (C2-C8)-alkinyl.
公开/授权文献
- US20030232802A1 Aryl and heteroaryl sulfonates 公开/授权日:2003-12-18
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