发明授权
- 专利标题： Combinatorial strategies for polymer synthesis
- 专利标题（中）： 聚合物合成的组合策略
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申请号： US09498554申请日： 2000-02-04
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公开(公告)号： US06943034B1公开(公告)日： 2005-09-13
- 发明人: James L. Winkler , Stephen P. A. Fodor , Christopher J. Buchko , Debra A. Ross , Lois Aldwin , Douglas N. Modlin
- 申请人： James L. Winkler , Stephen P. A. Fodor , Christopher J. Buchko , Debra A. Ross , Lois Aldwin , Douglas N. Modlin
- 申请人地址： US CA Santa Clara
- 专利权人： Affymetrix, Inc.
- 当前专利权人： Affymetrix, Inc.
- 当前专利权人地址： US CA Santa Clara
- 代理机构： Banner & Witcoff, Ltd.
- 主分类号： B01J19/00
- IPC分类号： B01J19/00 ; C07B61/00 ; C07H21/00 ; C07K1/04 ; C40B40/06 ; C40B40/10 ; C40B60/14 ; G01N35/10 ; G01N1/00
摘要：
A method for producing arrays by spacing a dispenser a distance from a surface of a support, dispensing a volume containing a compound in a single coupling step of less than 5 nl to occupy a localized area of less than 1 cm2 of the surface of the support, allowing the compound to bind directly or indirectly to the support and repeating the steps to produce an array of at least 100 ligands at a density of 1000 per cm2 or greater.
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