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发明授权
US06962702B2 Production and use of novel peptide-based agents for use with bi-specific antibodies 失效
用于双特异性抗体的新型基于肽的试剂的生产和使用

Production and use of novel peptide-based agents for use with bi-specific antibodies
摘要：
The present invention relates to a bi-specific antibody or antibody fragment having at least one arm that is reactive against a targeted tissue and at least one other arm that is reactive against a linker moiety. The linker moiety encompasses a hapten to which antibodies have been prepared. The antigenic linker is conjugated to one or more therapeutic or diagnostic agents or enzymes. The invention provides constructs and methods for producing the bispecific antibodies or antibody fragments, as well as methods for using them.
摘要（中）：

本发明涉及一种双特异性抗体或抗体片段，其具有至少一个对靶组织有反应性的臂，以及至少一个对接头部分具有反应性的其它臂。 接头部分包括已经制备抗体的半抗原。 抗原性接头与一种或多种治疗剂或诊断剂或酶缀合。 本发明提供了用于产生双特异性抗体或抗体片段的构建体和方法，以及使用它们的方法。

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