发明授权
US06974679B2 Support with collagen base for tissue engineering and manufacture of biomaterials
失效
支持用于组织工程和生物材料制造的胶原基质
- 专利标题： Support with collagen base for tissue engineering and manufacture of biomaterials
- 专利标题（中）： 支持用于组织工程和生物材料制造的胶原基质
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申请号： US10364223申请日： 2003-02-10
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公开(公告)号： US06974679B2公开(公告)日： 2005-12-13
- 发明人: Valerie Andre , Nabil Abdul Malak , Alain Huc
- 申请人： Valerie Andre , Nabil Abdul Malak , Alain Huc
- 申请人地址： FR Lyons
- 专利权人： Coletica
- 当前专利权人： Coletica
- 当前专利权人地址： FR Lyons
- 代理机构： Merchant & Gould P.C.
- 优先权： FR0006743 20000526; FR0006748 20000526
- 主分类号： A61L27/24
- IPC分类号： A61L27/24 ; A61L27/34 ; A61L27/36 ; A61L27/38 ; A61L27/40 ; A61L27/48 ; A61L27/56 ; A61L27/60 ; C12N5/00 ; C12N5/071 ; C12Q1/00 ; G01N33/50 ; C12Q1/02 ; A61F13/00
摘要：
The invention relates to a method of in vitro testing of the efficacy of a potentially active substance comprising monitoring the effect of said potentially active substance on an artificial skin, comprising a composite product forming a collagen support comprising at least one porous collagen layer covered on at least one side with a collagen membrane component selected from the group consisting of a collagen membrane prepared by compression of a collagen sponge at a pressure of at least about 50 bar and of a collagen membrane comprising a collagen film prepared by drying a collagen gel separately from the porous collagen layer, thereby providing a reliable method for finding new potentially active substances.