发明授权
US06979564B2 80090, human fucosyltransferase nucleic acid molecules and uses thereof
失效
80090,人岩藻糖基转移酶核酸分子及其用途
- 专利标题: 80090, human fucosyltransferase nucleic acid molecules and uses thereof
- 专利标题(中): 80090,人岩藻糖基转移酶核酸分子及其用途
-
申请号: US10080960申请日: 2001-10-19
-
公开(公告)号: US06979564B2公开(公告)日: 2005-12-27
- 发明人: Maria A. Glucksmann , Rachel Meyers
- 申请人: Maria A. Glucksmann , Rachel Meyers
- 申请人地址: US MA Cambridge
- 专利权人: Millennium Pharmaceuticals, Inc.
- 当前专利权人: Millennium Pharmaceuticals, Inc.
- 当前专利权人地址: US MA Cambridge
- 代理机构: Millennium Pharmaceuticals, Inc.
- 主分类号: C07K14/705
- IPC分类号: C07K14/705 ; C12N9/10 ; C12N9/16 ; C12N15/12 ; C07H21/04 ; C12N1/20 ; C12N15/00
摘要:
The invention provides isolated nucleic acids molecules, designated 80090, 52874, 52880, 63497, or 33425 nucleic acid molecules, which encode novel fucosyltransferase, seven transmembrane receptor, or RhoGAP family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 80090, 52874, 52880, 63497, or 33425 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which an 80090, 52874, 52880, 63497, or 33425 gene has been introduced or disrupted. The invention still further provides isolated 80090, 52874, 52880, 63497, or 33425 proteins, fusion proteins, antigenic peptides and anti-80090, 52874, 52880, 63497, or 33425 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.