Invention Grant
- Patent Title: Calcium-independent negative regulation by CD81 of receptor signalling
- Patent Title (中): 钙依赖性CD81受体信号的负调控
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Application No.: US10004562Application Date: 2001-12-05
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Publication No.: US07026283B2Publication Date: 2006-04-11
- Inventor: Tony Fleming , Jean-Pierre Kinet
- Applicant: Tony Fleming , Jean-Pierre Kinet
- Applicant Address: US MA Boston
- Assignee: Beth Israel Deaconess Medical Center, Inc.
- Current Assignee: Beth Israel Deaconess Medical Center, Inc.
- Current Assignee Address: US MA Boston
- Agency: Hamilton, Brook, Smith & Reynolds, P.C.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K39/00 ; C12N15/00
Abstract:
Calcium independent CD81 inhibition of IgE-mediated degranulation in mast cells, particularly through the FcγRIII and FcεRI receptors, is described, as well as methods of inhibiting allergic processes.
Public/Granted literature
- US20020182726A1 Calcium-independent negative regulation by CD81 of receptor signalling Public/Granted day:2002-12-05
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