- 专利标题： Modulators of leukocyte activation, compositions and methods of use
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申请号： US10112674申请日： 2002-03-29
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公开(公告)号： US07045308B2公开(公告)日： 2006-05-16
- 发明人: Brian Wong , Chong Alan Fu , Helena Mancebo , Xiulan X.Z. Zhou
- 申请人： Brian Wong , Chong Alan Fu , Helena Mancebo , Xiulan X.Z. Zhou
- 申请人地址： US CA South San Francisco
- 专利权人： Rigel Pharmaceuticals, Inc.
- 当前专利权人： Rigel Pharmaceuticals, Inc.
- 当前专利权人地址： US CA South San Francisco
- 代理机构： Townsend and Townsend and Crew LLP
- 主分类号： C12N15/12
- IPC分类号： C12N15/12 ; C12N15/63 ; C12N15/00 ; G01N33/53
摘要：
The present invention provides compositions and methods for modulating leukocyte activation. Nucleic acids encoding proteins and proteins so encoded which are capable of modulating leukocyte activation are provided. Compositions and methods for the treatment of disorders related to leukocyte dysfunction or dysregulation are also provided. Prophylactics and methods for the prevention of such disorders are also provided. Also provided are compositions and methods for diagnostic and prognostic determination of such disorders. Further provided are assays for the identification of bioactive agents capable of modulating leukocyte activation.
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