- 专利标题： Diaminediols for the treatment of Alzheimer's disease
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申请号： US10192625申请日： 2002-07-10
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公开(公告)号： US07067542B2公开(公告)日： 2006-06-27
- 发明人: Heinrich Josef Schostarez , Robert A. Chrusciel
- 申请人： Heinrich Josef Schostarez , Robert A. Chrusciel
- 申请人地址： US MI Kalamazoo
- 专利权人： Pharmacia & Upjohn Company
- 当前专利权人： Pharmacia & Upjohn Company
- 当前专利权人地址： US MI Kalamazoo
- 代理机构： McDonnell Boehnen Hulbert & Berghoff LLP
- 主分类号： A61K31/40
- IPC分类号： A61K31/40 ; A61K31/41 ; A61K31/435 ; C07D213/46 ; C07D207/333
摘要：
The present invention relates to compounds of formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.
公开/授权文献
- US20030083353A1 Diaminediols for the treatment of Alzheimer's disease 公开/授权日：2003-05-01
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