Invention Grant
US07078414B2 Derivatives of 3-guanidinocarbonyl-1-heteroaryl-pyrrole, preparation process and intermediates of this process, their use as medicaments, and pharmaceutical compositions comprising them
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3-胍基羰基-1-杂芳基吡咯的衍生物,该方法的制备方法和中间体,它们作为药物的用途,以及包含它们的药物组合物
- Patent Title: Derivatives of 3-guanidinocarbonyl-1-heteroaryl-pyrrole, preparation process and intermediates of this process, their use as medicaments, and pharmaceutical compositions comprising them
- Patent Title (中): 3-胍基羰基-1-杂芳基吡咯的衍生物,该方法的制备方法和中间体,它们作为药物的用途,以及包含它们的药物组合物
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Application No.: US10745909Application Date: 2003-12-23
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Publication No.: US07078414B2Publication Date: 2006-07-18
- Inventor: Heinz-Werner Kleemann , Pascal Desmazeau , Jean-Christophe Carry , Baptiste Ronan , Serge Mignani , Jean Bououerel , Arielle Genevois-Borella
- Applicant: Heinz-Werner Kleemann , Pascal Desmazeau , Jean-Christophe Carry , Baptiste Ronan , Serge Mignani , Jean Bououerel , Arielle Genevois-Borella
- Applicant Address: DE Frankfurt am Main
- Assignee: Sanofi-Aventis Deutschland GmbH
- Current Assignee: Sanofi-Aventis Deutschland GmbH
- Current Assignee Address: DE Frankfurt am Main
- Agent Joseph D. Rossi
- Priority: FR0208947 20020716
- Main IPC: A61K31/47
- IPC: A61K31/47 ; A61K31/40 ; C07D215/02 ; C07D301/27

Abstract:
The present invention relates to 3-guanidinocarbonyl-1-heteroaryl-pyrrole derivatives of formula (I) wherein R1 to R3 and Ar are as defined herein, pharmaceutical compositions comprising such derivatives, methods of treatment comprising administering such derivatives, and processes for their preparation
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