发明授权
- 专利标题: Infectious cDNA clone of GB virus B and uses thereof
- 专利标题(中): GB病毒B的感染性cDNA克隆及其用途
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申请号: US10009002申请日: 2000-06-02
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公开(公告)号: US07129342B1公开(公告)日: 2006-10-31
- 发明人: Jens Bukh , Masayuki Yanagi , Suzanne U. Emerson , Robert H. Purcell
- 申请人: Jens Bukh , Masayuki Yanagi , Suzanne U. Emerson , Robert H. Purcell
- 申请人地址: US DC Washington
- 专利权人: The United States of America as represented by the Department of Health and Human Services
- 当前专利权人: The United States of America as represented by the Department of Health and Human Services
- 当前专利权人地址: US DC Washington
- 代理机构: Knobbe, Martens, Olson & Bear, LLP
- 国际申请: PCT/US00/15293 WO 20000602
- 国际公布: WO00/75337 WO 20001214
- 主分类号: C07H21/00
- IPC分类号: C07H21/00 ; C12N15/51 ; C12N15/09 ; C12N7/02 ; C12N7/00 ; C12P21/00 ; C12Q1/70 ; C12Q1/68
摘要:
The present invention relates to nucleic acid sequence which comprises the genome of an infectious GB virus B clone. The invention also relates to the use of the nucleic acid sequence of the infectious GB virus B clone to indirectly study the molecular properties of HCV, and in the production of HCV/GBV-B chimeras. The invention further relates to the use of the infectious nucleic acid sequence of GB virus B clone and the HCV/GBV-B chimeras in the development of vaccines and therapeutics for HCV.
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